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. Author manuscript; available in PMC: 2015 Sep 15.
Published in final edited form as: Transplantation. 2014 Sep 15;98(5):578–584. doi: 10.1097/TP.0000000000000107

FIGURE 2.

FIGURE 2

Autologous islet damage and the impact of NFκB inhibitors. The plasma levels of C-peptide (A), proinsulin (B), and thrombin-antithrombin (TAT) (C) in an autologous islet tube model are shown. Solid line (black circle), solid line (open circle), and dotted lines show the control, withaferin A (WA), and CAY10512 (CAY) groups, respectively. Symbols indicate the P value compared to baseline within each group of control*, WA or CAY# and the significance levels: *P<0.05 and **<0.01. Also, the symbols indicate the P value when compared between the control and WA§ or CAY groups. Data express average ± SE based on 3 independent experiments. Repeated-measurement two-way ANOVA with Dunnett’s multiple comparison test was performed for statistical evaluation.