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. 2014 Oct 22;9(10):e109235. doi: 10.1371/journal.pone.0109235

Table 1. Distribution for selected demographic and health characteristics comparing esophageal, stomach, and liver cancer cases with controls.

Controls Cancer Cases
Esophageal Cancer Stomach Cancer Liver Cancer
(N, %) (N, %) One-Sided (N, %) One-Sided (N, %) One-Sided
(N = 415) (N = 218) P-value (N = 206) P-value (N = 204) P-value
Age *, mean ± SD 57.7±11.8 60.6±9.6 0.001 62.8±9.8 <0.001 53.9±13.0 <0.001
Sex *
Female 128 (30.8) 77 (35.3) 0.25 68 (33.0) 0.58 45 (22.1) 0.022
Male 287 (69.2) 141 (64.7) 138 (67.0) 159 (77.9)
BMI, mean ± SD 22.4±2.6 21.9±2.8 0.035 21.4±2.7 <0.001 21.5±2.7 <0.001
Education
Illiterate 73 (17.6) 83 (38.6) <0.001 66 (32.0) <0.001 44 (21.6) 0.19
Primary school 142 (34.2) 101 (47.0) 107 (51.9) 77 (37.8)
Middle school or higher 200 (48.2) 31 (14.4) 33 (16.0) 83 (40.7)
Smoking
Never 217 (52.4) 94 (44.6) 0.063 92 (45.8) 0.12 85 (44.3) 0.062
Ever 197 (47.6) 117 (55.5) 109 (54.2) 107 (55.7)
pack-years, mean ± SD 23.7±15.6 28.9±21.9 0.030 27.7±19.2 0.068 21.2±14.0 0.20
Alcohol drinking
Never 207(50.2) 116 (55.0) 0.015 111 (55.2) 0.70 87 (45.3) 0.13
Occasionally 72(17.5) 18 (8.5) 31 (15.4) 29(15.1)
Often 75(18.2) 37 (17.5) 32 (15.9) 51(26.6)
Everyday 58(14.1) 40 (19.0) 27 (13.4) 25(13.0)
H. pylori CagA status
+ 251 (68.8) 130 (64.7) 0.32
114 (31.2) 71 (35.3)
HBsAg status
+ 102 (24.6) 132 (64.7) <0.001
312 (75.4) 72 (35.3)
Anti-HCV status
+ 12 (2.9) 18 (9.0) 0.001
403 (97.1) 183 (91.0)
Plasma AFB1-albumin adduct levels (qunitile)
1 75 (19.9) 26 (14.4) 0.054
2 76 (20.2) 36 (19.9)
3 75 (19.9) 36 (19.9)
4 76 (20.2) 28 (15.5)
5 75 (19.9) 55 (30.4)

*: Matching factors.

: Two-sided P-values derived from t-tests for continuous variables and χ2 tests for categorical variables comparing cancer cases to controls.