Table 1. Inter-individual and intra-treatment variability of fluoxetine plasma concentrations.
Treatment | Samplesize | Mean | Median | Min | Max | RatioMax:Min | 25% | 75% |
10 µg/L – Rep A | 5 | 48.4 | 37.4 | 31.8 | 72.2 | 2.3 | 34.6 | 66.8 |
10 µg/L – Rep B | 5 | 46.4 | 44.0 | 21.1 | 84.7 | 4.0 | 33.8 | 54.3 |
10 µg/L – Rep C | 5 | 39.3 | 41.0 | 29.5 | 45.8 | 1.6 | 35.5 | 43.3 |
10 µg/L – Rep D | 4 | 31.7 | 27.4 | 24.5 | 47.6 | 1.9 | 24.7 | 38.8 |
10 µg/L – ALL FISH | 19 | 42.0 | 38.1 | 21.1 | 84.7 | 4.0 | 30.4 | 45.4 |
20 µg/L – Rep A | 5 | 105.1 | 97.9 | 64.9 | 147.4 | 2.3 | 86.9 | 127.5 |
20 µg/L – Rep B | 5 | 95.2 | 107.9 | 53.0 | 129.0 | 2.4 | 71.3 | 113.9 |
20 µg/L – Rep C | 5 | 95.5 | 84.9 | 59.1 | 158.5 | 2.7 | 70.2 | 115.3 |
20 µg/L – Rep D | 5 | 136.8 | 128.3 | 90.3 | 183.0 | 2.0 | 98.3 | 181.8 |
20 µg/L – ALL FISH | 20 | 108.1 | 100.9 | 53.0 | 183.0 | 3.5 | 81.1 | 128.7 |
38 µg/L – Rep A | 5 | 256.3 | 283.0 | 104.3 | 385.9 | 3.7 | 167.0 | 337.0 |
38 µg/L – Rep B | 3 | 451.7 | 342.8 | 265.9 | 746.3 | 2.8 | 285.1 | 645.4 |
38 µg/L – Rep C | 5 | 435.9 | 338.1 | 223.9 | 892.6 | 4.0 | 255.7 | 567.1 |
38 µg/L – Rep D | 5 | 428.0 | 391.6 | 116.3 | 881.4 | 7.6 | 235.6 | 577.0 |
38 µg/L – ALL FISH | 18 | 386.5 | 329.4 | 104.3 | 892.6 | 8.6 | 265.9 | 458.6 |
72 µg/L – Rep A | 5 | 700.4 | 723.7 | 645.3 | 728.5 | 1.1 | 669.1 | 727.7 |
72 µg/L – Rep B | 4 | 1249.7 | 867.4 | 632.0 | 2632.1 | 4.2 | 745.2 | 1754.3 |
72 µg/L – Rep C | 5 | 944.2 | 946.3 | 779.0 | 1051.7 | 1.3 | 875.2 | 1040.6 |
72 µg/L – Rep D | 4 | 877.6 | 659.4 | 527.9 | 1663.6 | 3.2 | 541.2 | 1214.0 |
72 µg/L – ALL FISH | 18 | 929.6 | 771.7 | 527.9 | 2632.1 | 5.0 | 677.0 | 946.3 |
The unit of the values indicated in the columns Mean, Median, Min, Max, 25%, and 75% is ng/mL.