Table 2. Inter-individual and intra-treatment variability of norfluoxetine plasma concentrations.
Treatment | Samplesize | Mean | Median | Min | Max | RatioMax:Min | 25% | 75% |
10 µg/L – Rep A | 5 | 189.7 | 215.2 | 98.4 | 272.1 | 2.8 | 122.1 | 242.6 |
10 µg/L – Rep B | 5 | 157.5 | 129.1 | 92.9 | 255.7 | 2.8 | 117.7 | 201.8 |
10 µg/L – Rep C | 5 | 167.4 | 173.5 | 98.5 | 214.6 | 2.2 | 150.8 | 190.2 |
10 µg/L – Rep D | 4 | 134.7 | 126.1 | 102.5 | 184.2 | 1.8 | 107.9 | 161.5 |
10 µg/L – ALL FISH | 19 | 163.8 | 168.3 | 92.9 | 272.1 | 2.9 | 116.6 | 207.0 |
20 µg/L – Rep A | 5 | 444.3 | 420.4 | 322.9 | 575.7 | 1.8 | 355.9 | 545.5 |
20 µg/L – Rep B | 5 | 378.9 | 436.8 | 190.1 | 490.0 | 2.6 | 281.1 | 472.1 |
20 µg/L – Rep C | 5 | 363.9 | 387.3 | 261.7 | 458.8 | 1.8 | 282.1 | 431.7 |
20 µg/L – Rep D | 5 | 544.4 | 477.8 | 349.6 | 869.2 | 2.5 | 384.8 | 689.0 |
20 µg/L – ALL FISH | 20 | 387.7 | 403.9 | 190.1 | 575.7 | 3.0 | 300.2 | 458.8 |
38 µg/L – Rep A | 5 | 788.1 | 847.1 | 462.9 | 930.6 | 2.0 | 721.8 | 901.6 |
38 µg/L – Rep B | 3 | 1127.8 | 1267.1 | 811.2 | 1305.1 | 1.6 | 925.2 | 1295.6 |
38 µg/L – Rep C | 5 | 883.9 | 773.7 | 487.8 | 1265.6 | 2.6 | 687.1 | 1170.7 |
38 µg/L – Rep D | 5 | 1176.4 | 1250.6 | 620.4 | 1627.1 | 2.6 | 948.1 | 1401.7 |
38 µg/L – ALL FISH | 18 | 979.2 | 911.2 | 462.9 | 1627.1 | 3.5 | 773.7 | 1265.6 |
72 µg/L – Rep A | 5 | 1528.4 | 1691.0 | 998.1 | 1805.1 | 1.8 | 1317.1 | 1744.6 |
72 µg/L – Rep B | 4 | 2556.8 | 1812.2 | 1328.2 | 5274.6 | 4.0 | 1461.0 | 3652.7 |
72 µg/L – Rep C | 5 | 1878.2 | 1811.8 | 1494.7 | 2419.3 | 1.6 | 1569.3 | 2158.2 |
72 µg/L – Rep D | 4 | 1674.3 | 1619.7 | 1003.1 | 2454.5 | 2.4 | 1237.2 | 2111.4 |
72 µg/L – ALL FISH | 18 | 1886.5 | 1707.7 | 998.1 | 5274.6 | 5.3 | 1471.2 | 2030.8 |
The unit of the values indicated in the columns Mean, Median, Min, Max, 25%, and 75% is ng/mL.