Table 4.
Results of multivariate survival analyses for TKI group according to the cox regression model
| Variables | TKI group | Non-TKI group | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OS | PFSI | PFSE | OS | PFSI | PFSE | |||||||
| RR | P value | RR | P value | RR | P value | RR | P value | RR | P value | RR | P value | |
| Extracranial lesions (yes/no) | 0.62 | 0.0007 | – | – | – | – | 0.80 | 0.0037 | – | – | – | – |
| TKI taking time (cut off 8 ms) | 0.58 | 0.0001 | 0.41 | 0.0008 | 0.73 | 0.0106 | – | – | – | – | – | – |
| Treatment option (WBRT vs. S/SRS) | – | – | – | – | 0.69 | 0.0103 | – | – | – | – | – | – |
| Smoking status (never) | – | – | – | – | – | – | 0.82 | 0.0127 | – | – | – | – |
| BM number (<3) | – | – | – | – | – | – | 0.84 | 0.0247 | – | – | – | – |
| BM size (<3 cm) | – | – | – | – | – | – | 0.79 | 0.0120 | – | – | – | – |
| T staging | – | – | – | – | – | – | – | – | – | – | 0.81 | 0.0087 |
| N staging | – | – | – | – | 0.76 | 0.0281 | 0.65 | 0.0000 | 0.78 | 0.0011 | 0.79 | 0.0020 |
OS overall survival, PFSI progression-free survival of intracranial disease, PFSE progression-free survival of extracranial disease