Table 4.
Multivariate Cox regression analysis of PFS and OS in second-line treatments
| PFS
|
OS
|
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Sex | 0.990 | 0.415–2.358 | 0.990 | 1.005 | 0.387–2.612 | 0.992 |
| Age | 0.732 | 0.455–1.177 | 0.198 | 0.645 | 0.396–1.049 | 0.077 |
| Response to first-line | 1.618 | 1.059–2.678 | 0.028 | 1.500 | 0.928–2.425 | 0.098 |
| Performance score | 1.824 | 1.083–3.072 | 0.024 | 1.957 | 1.179–3.246 | 0.009 |
| Second-line drug | 0.741 | 0.469 | 1.171 | 0.866 | 0.550–1.365 | 0.536 |
Abbreviations: CI, confidence interval; HR, hazard ratio; OS, overall survival; PFS, progression-free survival.