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. 2014 Oct 22;9(10):e110442. doi: 10.1371/journal.pone.0110442

Figure 2. HBV cccDNA CpG island III methylation is associated with serum HBsAg level.

Figure 2

(A) Correlation between serum HBsAg titers and cccDNA CpG island III methylation in patients with chronic HBV infection (r2 = 0.32, P<0.05). (B) The density of CpG island III methylation were significantly higher in patients with low serum HBsAg titer (Log10HBsAg<4) compared to those with high HBsAg level (Log10HBsAg≥4). Dots and squares represent single patient measurement. The median value is indicated with a long line.