Skip to main content
. 2014 Oct 22;9(10):e110442. doi: 10.1371/journal.pone.0110442

Figure 4. HBV CpG methylation is associated with patient age and liver fibrosis stage.

Figure 4

(A) CpG II methylation density differed significantly between patients with Knodell fibrosis stage S0-2 and S3-4. (B) Methylation of CpG III was markedly higher in patients with Knodell fibrosis stage S3-4 compared with those with fibrosis stage S0-2. (C) Patients with age ≥40 had higher density of CpG II methylation than and those with age <40.