Figure 2. Drug discovery against Dermo disease.

(A) Time line for the discovery of drugs against Dermo disease, starting when the etiological agent was described until this study. Most of the discoveries did happen after the development of the culture methodologies for Perkinsus spp. in 1993 and most studies have been carried out in in vitro cultures. (B) Percentage of the compounds active against Perkinsus based on their chemical nature. (C) Percentage of available compounds against Dermo tested in Perkinsus marinus and Perkinsus olseni.