Table 2. Associations of vaginal carriage of bacterial taxa with common vaginal infections.
Relative Risk (95% Confidence Interval) | |||
Trichomoniasis | Bacterial vaginosis | Yeast infection | |
“Ca. M girerdii” | 20.12 (7.75–48.34) | 0.88 (0.24–1.53) | 0.86 (0.00–1.98) |
M. hominis | 2.53 (0.85–6.83) | 2.08 (1.61–2.68) | 0.80 (0.44–1.30) |
U. parvum/U. urealyticum | 1.36 (0.40–3.49) | 0.62 (0.45–0.84) | 1.18 (0.74–1.75) |
Gardnerella vaginalis | 4.45 (0.91– Infinity*) | 7.17 (4.05–21.78) | 0.81 (0.54–1.32) |
Atopobium vaginae | 1.79 (0.70–9.10) | 5.02 (3.50–8.43) | 0.56 (0.35–0.83) |
BVAB2 | 0.66 (0.17–1.80) | 3.25 (2.54–4.30) | 0.45 (0.22–0.75) |
Bootstrap (n = 1,000) samples were selected from the outpatient clinic population to reflect the outpatient community composition. Median relative risk and 95% bootstrap confidence intervals are shown. A bacterial taxon was considered present in the mid-vaginal sample if at least 0.1% of the metagenomic 16S rRNA gene microbiome profile reads classified to the taxon. Vaginal infection was determined by clinical diagnosis using Amsel’s criteria for BV.
*For at least 2.5% of the bootstrap samples, all subjects with a trichomoniasis diagnosis were positive for G. vaginalis.