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. 2014 Oct 22;9(10):e110943. doi: 10.1371/journal.pone.0110943

Table 2. Associations of vaginal carriage of bacterial taxa with common vaginal infections.

Relative Risk (95% Confidence Interval)
Trichomoniasis Bacterial vaginosis Yeast infection
Ca. M girerdii” 20.12 (7.75–48.34) 0.88 (0.24–1.53) 0.86 (0.00–1.98)
M. hominis 2.53 (0.85–6.83) 2.08 (1.61–2.68) 0.80 (0.44–1.30)
U. parvum/U. urealyticum 1.36 (0.40–3.49) 0.62 (0.45–0.84) 1.18 (0.74–1.75)
Gardnerella vaginalis 4.45 (0.91– Infinity*) 7.17 (4.05–21.78) 0.81 (0.54–1.32)
Atopobium vaginae 1.79 (0.70–9.10) 5.02 (3.50–8.43) 0.56 (0.35–0.83)
BVAB2 0.66 (0.17–1.80) 3.25 (2.54–4.30) 0.45 (0.22–0.75)

Bootstrap (n = 1,000) samples were selected from the outpatient clinic population to reflect the outpatient community composition. Median relative risk and 95% bootstrap confidence intervals are shown. A bacterial taxon was considered present in the mid-vaginal sample if at least 0.1% of the metagenomic 16S rRNA gene microbiome profile reads classified to the taxon. Vaginal infection was determined by clinical diagnosis using Amsel’s criteria for BV.

*For at least 2.5% of the bootstrap samples, all subjects with a trichomoniasis diagnosis were positive for G. vaginalis.