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. 2014 Oct 22;9(10):e111089. doi: 10.1371/journal.pone.0111089

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© 2014 Phadke et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Copy number variation analysis of next generation sequencing reads confirms that 97/433 is a haploid MATα strain. Each of the 14 chromosomes is represented as a different color in a rainbow pattern. The average of the read coverage is a white horizontal bar. A log2 ratio close to zero for each chromosome compared to the genome average combined with FACS data support assignment as a haploid, euploid strain. (B) MATα comparison between 97/433 (VGIIIa), NIH312 (VGIIIb), and WM276 (VGI) revealed a 6 kb deletion in 97/433 and a larger intergenic region between the STE20 and ETF1 genes.