(A) Human and sheep-sized pod-IVR with four ov-IgG pods. The inset shows a close-up of a delivery channel and pod. The ring outer diameter is 56 mm. (B) Cross-sectional drawing [orientation indicated by arrows in (A)] of IVR through center of drug pod showing silicone ring, 1, containing embedded ov-IgG core, 4, with polylactic acid coating, 2, and delivery channel, 3, sealed in place with silicone backfill, 5. The ring cross-sectional diameter, D, is 8 mm. The delivery channel diameter, d, is 0.75 – 2.0 mm depending on desired ov-IgG release rate.