Table 20.

Comparison of naproxen to diclofenac and ibuprofen using rofecoxib as common comparator for major vascular events.

Intervention	Comparator	OR (intervention versus comparator)	95% CI (OR)
Naproxen	Rofecoxib	0.71	0.27, 1.83
Diclofenac	Rofecoxib	1.70	0.38, 7.56
Ibuprofen	Rofecoxib	0.22	0.02, 2.48

[Lisse et al. 2003; Schnitzer et al. 2005; Saag et al. 2000]

CI, confidence interval; OR, odds ratio.