Table 5.

Etoricoxib versus diclofenac for hypertension.

Study or subgroup	Etoricoxib		Diclofenac		Weight	Peto OR, Fixed, 95% CI
	Events	Total	Events	Total
EDGE 2005 [Baraf et al. 2007]	210	3593	95	3518	41.8%	2.15 [1.71, 2.71]
EDGE II [Krueger et al. 2008]	240	2032	197	2054	55.9%	1.26 [1.03, 1.54]
ZACHER 2003	8	256	9	260	2.4%	0.90 [0.34, 2.36]
Total (95% CI)		5881		5832	100.0%	1.56 [1.35, 1.81]
Total events	458		301

Heterogeneity: chi squared = 13.17, degrees of freedom = 2 (p = 0.001); I² = 85%. Test for overall effect: Z = 5.91 (p = 0.00001).

CI, confidence interval; OR, odds ratio.