Table 6.
Study or subgroup | Etoricoxib |
Diclofenac |
Weight | Peto OR, Fixed, 95% CI | ||
---|---|---|---|---|---|---|
Events | Total | Events | Total | |||
EDGE 2005 [Baraf et al. 2007] | 14 | 3593 | 17 | 3518 | 45.7% | 0.81 [0.40, 1.63] |
EDGE II [Krueger et al. 2008] | 21 | 2032 | 15 | 2054 | 52.8% | 1.41 [0.73, 2.73] |
ZACHER 2003 | 0 | 256 | 1 | 260 | 1.5% | 0.14 [0.00, 6.93] |
Total (95% CI) | 5881 | 5832 | 100.00% | 1.06 [1.66, 1.70] | ||
Total events | 35 | 33 |
Heterogeneity: chi squared = 2.37, degrees of freedom = 2 (p = 0.31); I2 = 15%. Test for overall effect: Z = 0.23 (p = 0.82).
CI, confidence interval; OR, odds ratio.