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. 2014 Aug;6(4):111–130. doi: 10.1177/1759720X14541668

Table 7.

Celecoxib versus diclofenac for major vascular events.

Study or subgroup Celecoxib
Diclofenac
Weight Peto OR, Fixed, 95% CI
Events Total Events Total
CAESAR 2009 [Dahlberg et al. 2009] 3 458 8 458 41.4% 0.40 [0.12, 1.31]
CONDOR 2010 [Chan et al. 2010] 8 2238 1 2246 34.2% 4.77 [1.29, 17.63]
McKenna et al. [2001] 0 201 2 199 7.6% 0.13 [0.01, 2.14]
SUCCESS-I [Singh et al. 2006] 3 8800 2 4394 16.9% 0.74 [0.12, 4.75]
Total (95% CI) 11697 7297 100.00% 0.95 [0.44, 2.04]
Total events 14 13

Heterogeneity: chi squared = 9.89, degrees of freedom = 3 (p = 0.02); I2 = 70%. Test for overall effect: Z = 0.13 (p = 0.90).

CI, confidence interval; OR, odds ratio.