Table 7.
Study or subgroup | Celecoxib |
Diclofenac |
Weight | Peto OR, Fixed, 95% CI | ||
---|---|---|---|---|---|---|
Events | Total | Events | Total | |||
CAESAR 2009 [Dahlberg et al. 2009] | 3 | 458 | 8 | 458 | 41.4% | 0.40 [0.12, 1.31] |
CONDOR 2010 [Chan et al. 2010] | 8 | 2238 | 1 | 2246 | 34.2% | 4.77 [1.29, 17.63] |
McKenna et al. [2001] | 0 | 201 | 2 | 199 | 7.6% | 0.13 [0.01, 2.14] |
SUCCESS-I [Singh et al. 2006] | 3 | 8800 | 2 | 4394 | 16.9% | 0.74 [0.12, 4.75] |
Total (95% CI) | 11697 | 7297 | 100.00% | 0.95 [0.44, 2.04] | ||
Total events | 14 | 13 |
Heterogeneity: chi squared = 9.89, degrees of freedom = 3 (p = 0.02); I2 = 70%. Test for overall effect: Z = 0.13 (p = 0.90).
CI, confidence interval; OR, odds ratio.