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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Dev Dyn. 2014 Aug 1;243(11):1391–1400. doi: 10.1002/dvdy.24165

Figure 8. Expression of canonical Wnt pathway genes is altered during corneal development in Pitx2-tko mice.

Figure 8

In situ hybridization was used to detect expression of the Dkk2 (A,C) and Axin2 (B,D) mRNA at e14.5. Dkk2 expression is not maintained in the corneal mesenchyme while Axin2 expression is elevated in both the corneal surface ectoderm and underlying mesenchyme of Pitx2-tko eyes. E, corneal ectoderm; M, corneal mesenchyme.