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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Biom J. 2014 Aug 14;56(6):1076–1092. doi: 10.1002/bimj.201300148

Table 4.

Simulated power of the genotypic TDT and the score test. The power was determined assuming either an additive or a dominant mode of inheritance and based on 105 simulated data sets consisting of the number of trios summarized in Table 2 for each of the settings in Table 2.

Genotypic TDT Score Test
RR MAF Additive Dominant Additive Dominant
1.05 0.01 0.801 0.801 0.800 0.800
0.10 0.799 0.798 0.800 0.802
0.20 0.801 0.800 0.799 0.799
0.50 0.801 0.800 0.800 0.799

1.20 0.01 0.800 0.800 0.801 0.801
0.10 0.801 0.799 0.799 0.800
0.20 0.799 0.798 0.798 0.801
0.50 0.799 0.801 0.799 0.800

1.30 0.01 0.800 0.800 0.800 0.800
0.10 0.798 0.802 0.799 0.798
0.20 0.799 0.800 0.801 0.798
0.50 0.800 0.800 0.798 0.800

1.40 0.01 0.800 0.798 0.800 0.801
0.10 0.800 0.798 0.800 0.800
0.20 0.799 0.799 0.800 0.800
0.50 0.802 0.800 0.799 0.801

1.50 0.01 0.800 0.803 0.798 0.799
0.10 0.798 0.799 0.800 0.801
0.20 0.797 0.800 0.802 0.798
0.50 0.798 0.800 0.798 0.798