Table 4. Genotype and allele frequencies of VEGF gene polymorphisms in AMD patients in comparison to controls.
| SNP | Genotype/allele | Patients n (%) | Controls n (%) | OR (95% CI) |
| rs1413711 | GG | 21 (25.6) | 34 (42.5) | 0.47 (0.24-0.91)a |
| GA | 2 (2.4) | 1 (1.3) | 1.98 (0.18-22.22) | |
| AA | 59 (72.0) | 45 (56.2) | 2.00 (1.04-3.84)a | |
| GG vs (GA+AA) | 2.25 (1.15-4.43)a | |||
| G | 44 (26.8) | 69 (43.1) | 0.48 (0.30-0.77)a | |
| A | 120 (73.2) | 91 (56.9) | 2.07 (1.30-3.30)a | |
| rs2146323 | CC | 16 (19.5) | 29 (36.3) | 0.43 (0.21-0.87)a |
| CA | 17 (20.7) | 20 (25.0) | 0.79 (0.38-1.64) | |
| AA | 49 (59.8) | 31 (38.7) | 2.35 (1.25-4.41)a | |
| CC vs (CA+AA) | 2.02 (0.99-4.16)a | |||
| C | 49 (29.9) | 78 (48.8) | 0.45 (0.28-0.71)a | |
| A | 115 (70.1) | 82 (51.2) | 2.23 (1.42-3.52)a | |
| rs3025033 | AA | 80 (97.6) | 79 (98.8) | |
| AG | 1 (1.2) | 1 (1.2) | ||
| GG | 1 (1.2) | 0 (0) | ||
| A | 161 (98.2) | 159 (99.4) | ||
| G | 3 (1.8) | 1 (0.6) |
VEGF: Vascular Endothelial Growth Factor; OR: Odds Ratio; CI: Confidence Interval; aThe significant P values.