Table 5. The genotype and allele frequencies of VEGF SNPs according to the type of AMD.
| Parameters | Patients n (%) | Controls n (%) | OR (95% CI) |
| rs1413711 | |||
| Wet AMD | |||
| GG | 17 (39.5) | 34 (42.5) | 0.89 (0.42-1.88) |
| GA | 0 (0) | 1 (1.3) | - |
| AA | 26 (60.5) | 45 (56.2) | 1.19 (0.56-2.50) |
| GG vs (GA+AA) | 1.13 (0.53-2.41) | ||
| G | 34 (39.5) | 69 (43.1) | 0.86 (0.51-1.47) |
| A | 52 (60.5) | 91 (56.9) | 1.16 (0.68-1.98) |
| Dry AMD | |||
| GG | 4 (10.3) | 34 (42.5) | 0.16 (0.05-0.48)a |
| GA | 2 (5.1) | 1 (1.3) | 4.27 (0.38-48.60) |
| AA | 33 (84.6) | 45 (56.2) | 4.28 (1.61-11.35)a |
| GG vs (GA+AA) | 6.47 (2.10-19.93)a | ||
| G | 10 (12.8) | 69 (43.1) | 0.19 (0.09-0.40)a |
| A | 68 (87.2) | 91 (56.9) | 5.16 (2.48-10.74)a |
| rs2146323 | |||
| Wet AMD | |||
| CC | 12 (27.9) | 29 (36.3) | 0.68 (0.30-1.53) |
| CA | 12 (27.9) | 20 (25.0) | 1.16 (0.50-2.68) |
| AA | 19 (44.2) | 31 (38.7) | 1.25 (0.59-2.65) |
| CC vs (CA+AA) | 1.27 (0.56-2.86) | ||
| C | 36 (41.9) | 78 (48.8) | 0.76 (0.45-1.28) |
| A | 50 (58.1) | 82 (51.2) | 1.32 (0.78-2.24) |
| Dry AMD | |||
| CC | 4 (10.3) | 29 (36.3) | 0.20 (0.07-0.62)a |
| CA | 5 (12.8) | 20 (25.0) | 0.44 (0.15-1.28) |
| AA | 30 (76.9) | 31 (38.7) | 5.27 (2.21-12.58)a |
| CC vs (CA+AA) | 4.29 (1.38-13.37)a | ||
| C | 13 (16.7) | 78 (48.8) | 0.21 (0.11-0.41)a |
| A | 65 (83.3) | 82 (51.2) | 4.76 (2.43-9.31)a |
VEGF: Vascular Endothelial Growth Factor; OR: Odds Ratio; CI: Confidence Interval; aThe significant P values.