Table 3.

Optimized values of parameters for MDM in vitro cultures (with reference for initial estimate).

Proliferative index	0.23	[39]
Apoptotic index	0.11	[39]
TNF production rate∗	2.671 × 10−10 nmol/min	[10]
IL-6 production rate∗	7.0962 × 10−10 nmol/min	[10]
IL-8 production rate∗	4.34 × 10−8 nmol/min	[10]
IL-10 production rate∗	9.458 × 10−10 nmol/min	[40]

*Cytokine production rates represent the rate for 10⁶ cells.