Figure 1.

Hepatic histopathologic severity in A. phagocytophilum-infected mice significantly increases after day 4 of infection. The severity scores reflect the degree of histopathologic inflammatory infiltration and underlying tissue injury in the liver, as a surrogate for systemic inflammatory injury, and as normalized to mock-infected controls. The horizontal bar represents the median severity rank, the box borders represent the 1^st and 3^rd rank quartiles, and the bars represent the minimum and maximum rank scores at each time interval.