Table 1.

Features of subunits of the human NRZ and RZZ complexes.

Proteins	Binding regions with partners	Structural features
ZW10 (779 aa*)	1–170 aa: RINT1, dynamitin 1–82 aa: ZWINT	Putative coiled-coil regions** (13–38 aa, 53–83 aa, 107–130 aa, 356–383 aa, 616–636 aa)
RINT1 (792 aa)	1–264 aa: ZW10, COG1	Putative coiled-coil regions (60–92 aa, 101–126 aa, 163–183 aa)
	151–256 aa: UVRAG
	358–440 aa: RBL2/p130
	257–792 aa: Rad50
NAG (2371 aa)	1036–2371 aa: ZW10-RINT1	β-propeller (1–420 aa)
		Sec39-like (734–1355 aa)
ROD (2209 aa)	1–350 aa: Zwilch	β-propeller (1–390 aa)
		Sec39-like (557–1153 aa)
Zwilch (591 aa)	Not determined	Putative coiled-coil regions (69–89 aa, 290–311 aa)

^*aa, amino acids.

^**window size = 21.