Table 2.

Ethnicity and cytochrome enzyme metabolic action

Ethnicity	CYP2D6		CYP3A4		CYP1A2
	PM	UM	PM	UM	PM	UM
Caucasian	8%33,34	1%–10%163	2%–9.6%164	14%162	NSD	NSD
African	3%–8%33,34	2%–29%165	26%–67%164	67%162	NSD	NSD
Asian	6%–10%33,34	0%–2%	0%–22%164	NSD	5%166	NSD
Japanese	0.39%35	NSD	NSD	NSD	14%166	NSD
Korean	0.22%36	NSD	NSD	NSD	NSD	NSD
Australian	NSD	NSD	NSD	NSD	5%7	NSD

Abbreviations: PM, poor metabolizers; UM, ultrafast metabolizers; NSD, no study done.