TABLE 1.
The baseline characteristics of the PAD patients categorized by tertiles of the omega-3 index.
| Characteristics | Tertile I 3.7 ± 0.3 (n=21) |
Tertile II 4.5 ± 0.3 (n=21) |
Tertile III 6.8 ± 2.0 (n=21) |
P-value |
|---|---|---|---|---|
| Age, Mean ± SD- | 64 ± 8 | 68 ± 9 | 70 ± 8 | .05 |
| Male Sex (%) | 21 (100) | 21 (100) | 21 (100) | N/A |
| Caucasian | 15 (71) | 16 (76) | 15 (71) | 1.0 |
| Rutherford Classification | 1.9 ± 0.8 | 2.4 ± 0.9 | 2.1 ± 0.9 | .23 |
|
Comorbidities
| ||||
| Hypertension | 19 (90) | 18 (86) | 21 (100) | .35 |
| Hyperlipidemia | 18 (86) | 18 (86) | 19 (90) | 1.0 |
| History of CAD | 6 (29) | 6 (29) | 10 (48) | .37 |
| Diabetes Mellitus | 5 (24) | 6 (29) | 9 (43) | .49 |
| History of previous lower extremity bypass | 4 (19) | 5 (24) | 1 (5) | .31 |
| History of previous lower extremity percutaneous procedure | 7 (33) | 5 (24) | 7 (33) | .83 |
| Current and past history of smoking | 21 (100) | 21 (100) | 17 (81) | .03 |
|
Medications
| ||||
| Aspirin | 14 (67) | 11 (55) | 13 (62) | .76 |
| Ace-inhibitor | 7 (33) | 7 (35) | 10 (48) | .65 |
| β-Blocker | 13 (62) | 7 (35) | 14 (67) | .10 |
| Statin | 19 (90) | 16 (80) | 19 (90) | .57 |
| Anthropometric measures and behavioral health | ||||
|
| ||||
| Body-Mass index (BMI) | 25 ± 4 | 28 ± 4 | 28 ± 5 | .08 |
| Waist-hip ratio | 0.98 ± 0.04 | 1.02 ± 0.07 | 1.00 ± 0.04 | .20 |
| PHQ-9 | 11 ± 7 | 2 ± 3 | 5 ± 7 | .03 |
Values as “mean +/− SD” or “n (%)”. The omega-3 index is the sum of EPA+DHA in RBC membranes.