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. 2014 Oct 3;87(1043):20140359. doi: 10.1259/bjr.20140359

Table 3.

Apparent diffusion coefficient (ADC) values of tumours and benign tissues before and after intensity-modulated radiotherapy (IMRT) (×10−3 mm2 s−1)

Time of ADC measurement ADC value × 10-3 mm2 s−1, mean ± standard deviation (range)
Tumours (n = 78) Benign tissues (n = 31)
Pre-IMRT overall 1.04 ± 0.18 (0.69–1.49) 1.59 ± 0.17 (1.34–2.01)
 Non-recurrence group (n = 65) 1.05 ± 0.18 (0.69–1.49)  
 Recurrence group (n = 13) 1.00 ± 0.17 (0.74–1.27)  
Post-IMRT overall 1.45 ± 0.15 (1.06–1.78) 1.51 ± 0.13 (1.25–1.78)
 Non-recurrence group 1.49 ± 0.12 (1.14–1.78)  
 Recurrence group 1.27 ± 0.14 (1.06–1.53)  

Comparison of the mean ADC values of tumours: the mean post-IMRT ADC value of the recurrence group was significantly lower than that of the non-recurrence group; p < 0.001. After IMRT there was no significant difference in ADC values between the benign tissues and tumours of non-recurrence group; p = 0.47.