. Author manuscript; available in PMC: 2014 Oct 23.

Published in final edited form as: Vasc Med. 2013 Jul 8;18(4):176–184. doi: 10.1177/1358863X13493825

Table 2.

Association between incident symptomatic PAD events and subsequent cardiovascular events in patients with coronary artery disease^*

Cardiovascular outcome event	Base model^**			Full model^***
Cardiovascular outcome event	Hazard Ratio	95% CI	p-value	Hazard Ratio	95% CI	p-value
Composite endpoint	2.7	1.6, 4.4	0.0001	1.7	1.0, 2.9	0.04
Death	3.2	2.2, 4.7	<0.0001	1.8	1.2, 2.7	0.006
MI	3.8	1.6, 8,7	0.002	2.1	0.8, 5.4	0.11
CHF	2.2	0.9, 5.5	0.09	1.0	0.4, 2.5	0.996
Stroke/TIA	0.8	0.1, 6.2	0.87	0.6	0.1, 4.3	0.60
Revascularization	3.4	1.4, 8.5	0.008	3.0	1.2, 7.7	0.02

CI, confidence interval.

This is taken from the following number of events (Composite endpoint=474; death=340; MI=118; CHF=152; stroke/TIA=58; coronary revascularization=141).

excluding patients with a baseline history of PAD.

^**

Adjusted for age, sex, and race

^***

Included age, sex, race, and all variables that changed the effect size for incident PAD by >5%: traditional risk factors for PAD (smoking, diuretics), inflammatory markers (IL-6, TNF-a, CRP, fibrinogen) and glycemic control/insulin resistance (hemoglobin A1c).