Fig 2.

Boxplot of the white matter abnormality scores for the 4 ELBW infant groups show that the more previous brain hemorrhage, the more white matter abnormality at term-equivalent age. A score of 6 means normal white matter. Any score greater than 6 means abnormality. The line in the middle for each box is the median score for each group, and the box contains scores in 25–75 percentiles. Minimum/maximum scores in each group are also marked. A 1-way ANOVA revealed the significant effect (P < .001) of brain hemorrhage on white matter abnormality score at term-equivalent age in ELBW infants. ELBW_NO: ELBW infants without old blood product deposition on MR imaging at term-equivalent age; ELBW_BD: ELBW infants with old blood product on MR imaging but no IVH diagnosis by sonography; ELBW_12: ELBW infants with grades 1 or 2 IVH diagnosis; ELBW_34: ELBW infants with grades 3 or 4 IVH diagnosis.