Table 1.
Neuroimaging abnormality patterns in three variants of primary progressive aphasia for imaging-supported diagnosis (see: [1]).
Variant | MRI | SPECT/PET | |
---|---|---|---|
Non-fluent | Predominant left posterior fronto-insular atrophy | or | Predominant left posterior fronto-insular hypoperfusion or hypometabolism |
Semantic | Predominant anterior temporal lobe atrophy | or | Predominant anterior temporal hypoperfusion or hypometabolism |
Logopenic | Predominant left posterior perisylvian or parietal atrophy | or | Predominant left posterior perisylvian or parietal hypoperfusion or hypometabolism |
MRI – magnetic resonance imaging; PET – positron emission tomography; SPECT – single-photon emission computerized tomography.