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. 2014 Oct 3;2:144. doi: 10.1186/s40478-014-0144-4

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© Kreft et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cortical kif21b is significantly increased in younger Alzheimer patients compared with MS and NDC. A) Kif21b expression is significantly increased in AD patients younger than 62 years at death compared with MS and NDC younger than 62 yrs and in AD patients between 62-72 yrs compared with MS patients in the same age category. B) No significant differences were found in the expression of NeuN, a neuron specific marker, in the youngest two age categories. However, NeuN expression significantly decreased in elderly AD patients compared with NDC.