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. 2014 Oct 3;2:144. doi: 10.1186/s40478-014-0144-4

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© Kreft et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of kif21b, but not other kinesins increases upon astrocyte activation. The astrocytoma cell line U251 was stimulated with IL-1β and IFN-γ for 48 h in three independent experiments in duplo. A) Kif21b expression increased approximately nine-fold upon stimulation, whereas B) kif1bα did not change C) and kif5a slightly decreased. Next, primary isolated astrocytes of a NDC were also stimulated in one experiment in triplo and similar changes in kinesin expression were found (D-F).