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. 2014 Oct 13;63(11):3686–3698. doi: 10.2337/db14-0513

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© 2014 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

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BAT and beige fat gene changes in adipose tissue biopsies across 4-month acclimatization. A: Changes in general BAT gene expression (general BAT genes are defined as genes ascribed to general BAT function and do not indicate their developmental origin). Expression of CIDEA, but not others, changed significantly (P = 0.04) during acclimatization across 4-month period. B: Changes in classic BAT gene expression. Classic BAT genes are defined as those expressed in interscapular BAT in animals or human infants (50). C: Changes in beige fat gene expression. Beige fat genes are defined as those expressed in inducible brown adipocytes, also known as brite or beige adipocytes, found within WAT depots. No significant changes were observed in classic BAT or beige fat genes across temperature acclimation.