Table 2.
Mannose-Binding Lectin (MBL) Serum Concentrations Across MBL2 Haplotypes in Patients With Clostridium difficile Infection and Antibiotic-Associated Diarrhea
| Haplotype | HYPA | LYPA | LYQA | LXPA | HYPD | LYPB | LYQC |
|---|---|---|---|---|---|---|---|
| Presence of haplotype | |||||||
| No. (% frequency) | 213 (29) | 44 (6) | 143 (19) | 170 (23) | 55 (7) | 108 (15) | 11 (1) |
| Median, ng/mL (range) | 612 (17–3981) | 587 (0–2500) | 529 (0–3981) | 428 (0–2968) | 157 (0–815) | 73 (0–637) | 48 (0–492) |
| Absence of haplotype | |||||||
| No. (% frequency) | 198 (9) | 367 (17) | 268 (13) | 241 (11) | 356 (17) | 303 (14) | 400 (19) |
| Median: absence, ng/mL (range) | 171 (0–2374) | 388 (0–3981) | 324 (0–2968) | 377 (0–3981) | 484 (0–3981) | 568 (0–3981) | 420 (0–3981) |
| P valuea | <.001 | .04 | <.001 | .34 | <.001 | <.001 | .001 |
a P values were calculated using a Mann–Whitney test comparing mannose-binding lectin serum concentrations against the presence/absence of each individual haplotype.