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. 2014 Oct 23;10(10):e1003871. doi: 10.1371/journal.pcbi.1003871

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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The five subclasses of PBMCs are: DNA (containing HIV-1 DNA, black circles), Low (containing solely HIV-1 UsRNA, red diamonds), Mid (containing only HIV-1 MsRNA-tatrev or MsRNA-nef, green crosses), High (containing elevated levels of both HIV-1 MsRNA-tatrev and MsRNA-nef, blue triangles) and Extra (carrying virion-enclosed HIV-1 RNA, chocolate squares). Thick lines and symbols represent the geometric means of the five patients from the study by Fischer et al. [12]. Thin transparent lines for each color represent the original data for each subclass of cells of each individual patient. The dashed line represents the limit of detection that was set at 50% of the lowest measured cell count. Measurements below this threshold were assumed to be at 50% of the detection limit to include them in the mean.

Inline graphic — The five subclasses of PBMCs are: DNA (containing HIV-1 DNA, black circles), Low (containing solely HIV-1 UsRNA, red diamonds), Mid (containing only HIV-1 MsRNA-tatrev or MsRNA-nef, green crosses), High (containing elevated levels of both HIV-1 MsRNA-tatrev and MsRNA-nef, blue triangles) and Extra (carrying virion-enclosed HIV-1 RNA, chocolate squares). Thick lines and symbols represent the geometric means of the five patients from the study by Fischer et al. [12]. Thin transparent lines for each color represent the original data for each subclass of cells of each individual patient. The dashed line represents the limit of detection that was set at 50% of the lowest measured cell count. Measurements below this threshold were assumed to be at 50% of the detection limit to include them in the mean.