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COX-2 expression induced by KA-treatment was reduced in TonEBP (+/−) mice. (a) Western blotting analysis of COX-2. Hippocampal tissues were extracted from wild-type (WT), TonEBP (+/−), KA-treated WT, or KA-treated TonEBP (+/−) mice. Values were normalized to β-actin. Data are shown as mean±S.E.M. *P<0.05 versus WT control (CTL). (b) Representative immunofluorescence images of TonEBP (green) and COX-2 (red) in the CA3 region of the hippocampus. Scale bar=50 μm
