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. 2014 Jul-Sep;6(3):41–51.

Table 1.

Change of mRNA expression of a number of genes in cells inoculated with mycoplasma in 3-7 days after contamination

Mycoplasma Cell culture Induction of mRNA expression Suppression of mRNA expression Reference
M. fermentans Epithelial cells of
prostate HPV E7
14 cytokines TGFβ1, TGFβ3 [41]
M. genitalium 12 cytokines GM-CSF, IL-1Ra, M-CSF
M. hominis 12 cytokines TGFβ2
M. penetrans 14 cytokines TGFβ2
M. fermentans Epithelial cells of
cervical canal HPV
E6
17 cytokines 0 [41]
M. genitalium 13 cytokines G-CSF, IL-1Ra
M. hominis 13 cytokines IL-1α, IL–1β
M. penetrans 15 cytokines TGFβ2,TGF-β3
M. synoviae Chicken macrophages
MDM
Cytokines, lysozyme, apoptosis
inhibitor, 11 enzymes, 4 types of
receptors, 10 proteins of the signaling
system
ovotransferrin, glutathione
S-transferase, guanylate-binding
protein
[42]
M. fermentans
incognitas
Mice embryoblast
C3H
92 genes encoding oncogenes and
tumor suppressors
43 genes encoding oncogenes
and tumor suppressors
[40]
Phytoplasma Paulownia culture 769 genes 437 genes [45]