Table S7.
Post-study mortality rates
| Initiation sample
|
Step-up sample
|
|||
|---|---|---|---|---|
| Extrafine BDP (n=334) |
Fluticasone (n=334) |
Extrafine BDP (n=189) |
Fluticasone (n=189) |
|
| Follow-up time in yearsa mean (SD) | 6.6 (2.5) | 7.0 (2.6) | 6.4 (2.3) | 7.2 (2.3) |
| Number of deaths, n (%) | 58 (17.4) | 64 (19.2) | 26 (13.8) | 39 (20.6) |
| All-cause mortality, adjusted HR (95% CI) | 1.07 (0.68–1.70)b | 1.00 | 1.23 (0.61–2.47)c | 1.00 |
Notes: The study was not designed to evaluate mortality rates during treatment, as patients had to be alive throughout the 2 year outcome period to be eligible for the study.
a
Follow-up time from index date until censored or the end of the study period (end of 2010). Cox proportional hazards model
b
adjusted for Charlson comorbidity index score and smoking status
c
adjusted for age and cardiac disease diagnosis or therapy.
Abbreviations: BDP, beclomethasone dipropionate; CI, confidence interval; HR, hazard ratio; SD, standard deviation.