Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Oct 23;10(10):e1004646. doi: 10.1371/journal.pgen.1004646

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 McCole et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) ^classicalCNVs are identified solely by variation among individuals in the copy number of genomic regions. (B) ^{de nov}°CNVs are present in an individual but not in the soma of either of the parents. (C) ^cancerCNAs are copy number alterations that occur specifically in the cancer cells (orange) of an individual and, therefore, are absent from the healthy cells of the same individual (black). In this study we required ^cancerCNAs to be recurrent between individuals. (D) ^somaticCNVs are defined by regions that vary in copy number among the healthy somatic cells of an individual. (E) ^iPSCNVs are defined by regions that vary in copy number within a population of iPS cells and which are not detectable in the fibroblast cells from which the iPS cells were derived.