|
Krt76
|
Keratin 76 |
palate, paw pad, oral epithelium, fore stomach |
intermediate filament, cytoskeleton, structural molecule activity |
palatal keratin |
behavior, integument |
MP:0001510 - abnormal coat appearance MP:0010179 - rough coat MP:0000416 - sparse hair MP:0000575 - dark foot pads |
|
Lrig1
|
leucine-rich repeats and immunoglobulin-like domains 1 |
most tissues including skin |
Integral to membrane, tumor suppressor |
Marker of hair follicle junctional zone stem cells |
adipose, growth/size, hearing/vestibular/ear, homeostasis, immune, integument, limbs/digits/tail, skeleton, vision/eye |
MP:0001191 - abnormal skin condition MP:0001192 - scaly skin |
|
Myo5a
|
Myosin VA |
brain, cartilage, pituitary gland, spinal cord, urinary system |
ATP-dependant motor protein, actin filament based movement |
melanocyte differentiation, pigmentation |
integument, mortality/aging, pigmentation |
MP:0000371 - abnormal coat/hair pigmentationMP:0002075 - diluted coat color |
|
Myo6
|
Myosin V1 |
cochlear hair cells* |
sensory perception of sound, auditory receptor cell differentiation, signal transduction |
unknown |
behavior, integument, skeletal, homeostasis/metabolism, immune |
MP:0000367 - abnormal coat/hair morphology MP:0000418 - localized hair loss |
|
Mysm1
|
Histone H2A deubiquitinase |
most tissues including skin |
histone deubiquitination, postivie regulator of transcription |
unknown |
adipose, behavior, cellular, craniofacial, growth/size, hematopoietic, homeostasis, immune, integument, limbs/digits/tail, mortality/aging, other, pigmentation, skeleton, vision/eye |
MP:0000373 - belly spot MP:0000574 - abnormal foot pad morphology MP:0000575 - dark foot pads |
|
Nsun2
|
NOL1/NOP2/Sun domain family member 2 |
ubiquitous |
RNA methyltransferase, cell cycle, cell division |
Hair follicle stem cell self-renewal |
adipose, behavior, craniofacial, growth/size, hematopoietic, homeostasis, integument, limbs/digits/tail, reproductive, skeleton, vision/eye |
MP:0001510 - abnormal coat appearance, |
|
Prkab1
|
protein kinase, AMP-activated, beta 1 non-catalytic subunit |
brain, eye, liver, skull |
fatty acid biosynthetic process, fatty acid metabolic process, lipid metabolic process |
unknown |
resistance to diet induced obesity, liver steatosis, and hyperinsulinemia |
MP:0000579 - abnormal nail morphology |
|
Sparc
|
secreted acidic cysteine rich glycoprotein |
ubiquitous |
bone and lung development, cell migration, tissue remodelling |
unknown |
craniofacial, skeleton, vision/eye |
MP:0010096 - abnormal incisor color |
|
Vangl1
|
vang-like protein 1 |
skin, brain, cartilage, colon, bladder, eye, kidney, bone, thyroid, intestine, heart, lung, oesophagus, parathyroid, spinal cord |
development, integral to membrane, protein binding |
unknown |
hematopoietic system, homeostasis/metabolism, integument |
MP:0003849 - greasy coat, MP:0000574 - abnormal foot pad morphology, MP:0000575 - dark foot pads |
