Table 3.
Multivariable Exact Logistic Regression Analyses of Risk Factors for Uncontrolled Seizures and Seizure After Antiseizure Drug Withdrawal.
Variable | P Value | Odds Ratio (95% CI) |
---|---|---|
Uncontrolled seizures | ||
Gender (male vs female) | .02 | 0.18 (0.04, 0.77) |
Gabapentin vs other AED | .06 | 0.16 (0.02, l.ll) |
Seizure control with first AED vs no control | .08 | 0.26 (0.06, 1.15) |
Longer vs short interval from DX to first seizure | .09 | l.02 (0.99, l.04) |
Intractable seizures | ||
Age ≤3 vs >3 years at cancer diagnosis | .01 | 9.6 (l.6, 56.8) |
CNS leukemia at diagnosis vs normal CNS | .02 | 0.l (0.02, 0.69) |
Seizure relapse after AED withdrawal | ||
Seizure control with first AED vs no control | .04 | −2.7 (−5.2, −0.2) |
Focal neurologic deficit present vs absent | .08 | 3.1 (−0.3, 6.4) |
Radiation treatment vs no treatment | .05 | 2.5 (−0.3, 5.3) |
Abbreviations: AED, antiepilepsy drug; CNS, central nervous system; DX, diagnosis; vs, versus.