Table 2. The GHSXG and the YASH Motifs of Select Acyltransferases are Responsible for ACP vs CoA Discrimination.

AT Domain	Substrate	GHSXG Motif					YASH Motif
ZmaA-AT	Hydroxymalonyl-ACP	G190	Y	S	F	G	G294	A	A	H
ZmaF	Aminomalonyl-ACP	G90	Y	S	L	G	G198	P	F	H
ZmaK-AT	Malonyl-CoA	G1644	H	S	I	G	H1742	A	F	H
FabD (E. coli)	Malonyl-CoA	G90	H	S	L	G	V198	P	S	H
FabD (S. coelicolor)	Malonyl-CoA	G95	H	S	V	G	G198	A	F	H
DEB PKS-AT3	Methylmalonyl-CoA	G649	H	S	Q	G	Y751	A	S	H
DEB PKS-AT5	Methylmalonyl-CoA	G640	H	S	Q	G	Y742	A	S	H