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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Am J Med Sci. 2014 Nov;348(5):371–376. doi: 10.1097/MAJ.0000000000000262

Table 3.

Univariable and multivariable analysis of risk factors for mortality

Univariable analysis
Odds
Ratio		 95%
Confidence Interval
Guideline-recommended vancomycin dosing 0.70 0.32–1.58
Pitt Bacteremia Score of 4 or greater 1.80 0.86–3.78
Concomittantnephrotoxins (aminoglycosides, intravenous
contrast, vasopressors)		 1.38 0.64–2.97
Weight of 100kg or greater 1.53 0.66–3.56
Age greater than 65 years 2.91 1.36–6.27
Vancomycin trough concentration greater than 15 mg/dl 2.03 0.91–4.56
Development of nephrotoxicity 3.59 1.67–7.74
Multivariable analysis
Odds
Ratio		 95%
Confidence Interval
Guideline-recommended vancomycin dosing 0.54 0.22–1.36
Development of nephrotoxicity 2.87 1.21–6.78
Pitt Bacteremia Score of 4 or greater 2.94 1.05–8.22
Age greater than 65 years 2.50 1.03–6.07