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. 2014 Jun 20;155(9):3227–3237. doi: 10.1210/en.2014-1016

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Copyright © 2014 by the Endocrine Society

This article has been published under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Copyright for this article is retained by the author(s). Author(s) grant(s) the Endocrine Society the exclusive right to publish the article and identify itself as the original publisher.

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Figure 6. — ³H-25OHD₃ uptake in WT and VDRKO myofibers. A, Preincubation of WT myofibers with 1,25(OH)₂D resulted in 40% greater ³H-25OHD₃ uptake compared with WT myofibers preincubated with control solution (P < .005). No such increase in ³H-25OHD₃ uptake in response to 1,25(OH)₂D was seen in VDRKO mice (n = 3 mice per group). B, In C2C12 myotubes, DIDS reversed the 1,25(OH)₂D-mediated increase in uptake of ³H-25OHD₃. cpm, counts per minute.