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. 2014 Feb 11;99(6):E953–E961. doi: 10.1210/jc.2013-1569

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Copyright © 2014 by the Endocrine Society

This article has been published under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Copyright for this article is retained by the author(s). Author(s) grant(s) the Endocrine Society the exclusive right to publish the article and identify itself as the original publisher.

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Figure 3. — Time profiles of circulating kisspeptin and other reproductive hormones during an infusion of kisspeptin-54 to women with HA. Five women with HA each underwent an iv infusion of saline vehicle (gray) or 0.01 (green), 0.03 (orange), 0.10 (blue), 0.30 (purple), or 1.00 (red) nmol/kg/h kisspeptin-54. between 0 and 480 minutes (except a 600 min duration with 1.0 nmol/kg/h kisspeptin-54) commencing at 0 minutes. Data presented are mean ± SEM for plasma kisspeptin IR in picomoles per liter (A), serum LH in international units per liter (B), serum FSH in international units per liter (C), and serum E2 in picomoles per liter (D). *, P < .05; **, P < .01; ***, P < .001.