Table 2.

Amino acid positional changes in central channel neck region RMS Å

Conformer	W298–L65	Q168–W392	W392–I171	F24–N117	F24–I171	F24–W416
3a	5.8	3.38	3.45	7.46	4.48	3.56
3b	5.59	3.38	3.45	6.10 (1.36)	4.49	3.56
4a	5.02	8.38	10.81	6.48	3.71 (0.78)	3.82 (0.3)
4b	5.08	8.35	10.8	6.52	4.82	3.83
4c	5.04	8.48 (5.1)	10.92 (7.47)	6.52 (0.98)	3.82	3.8
4Gby	5.07	3.8	9.46	6.68	6.68 (2.97)	3.64
4GBz	4.77	4.93	12.73 (3.3)	6.41	6.41	3.68
4GC0	5.36 (0.6)	3.8 (4.7) (1.13)	10.75 (1.98)	5.39 (1.29)	5.39 (1.29)	3.46 (0.37)