Table 1.
Demographic Data and Thyroid Function Test Results for 523 Women at 28 Weeks of Pregnancy and 4.9 ± 1.6 Years After Pregnancy
| During Pregnancy | Postpregnancy | Pa | |
|---|---|---|---|
| Subject characteristics | |||
| Age, y | 32 (29–35) | 37 (33–40) | |
| Body mass index, kg/m2 | 26.5 (24.4–29.7) | 23.7 (21.8–26.8) | <.001 |
| Smokingb | 46/454 (10) | 62/454 (14) | .009 |
| Pregnancy details | |||
| Primipara | 236 (45) | ||
| Subsequent pregnancies (n = 521b) | |||
| 0 | 294 | ||
| 1 | 207 | ||
| 2 | 18 | ||
| >2 | 2 | ||
| Cesarean deliveryb,c | 108/520 (21) | 55/220 (25) | |
| Thyroid function tests and TPO-Abs | |||
| TSH, mIU/L | 1.81 (1.37–2.45) | 1.89 (1.32–2.63) | .01 |
| FT4, pmol/L | 12.1 (11.2–13.0) | 14.8 (13.6–16.0) | <.001 |
| FT3, pmol/L | 4.1 (3.9–4.4) | 4.5 (4.2–4.8) | <.001 |
| TPO-Ab positiveb | 27/520 (5.1) | 64/520 (12.3) | <.001 |
| Receiving l-thyroxine | NA | 8/523 (1.5) |
Abbreviation: NA, not applicable. Data are presented as median (interquartile range) or n (%).
a
P values were determined by the Wilcoxon or McNemar test for related data and are not presented for age as all patients were older postpregnancy.
b
Some missing data.
c
Postpregnancy number represents any women who had a cesarean delivery in a subsequent pregnancy.