Table 1.
Demographics and Baseline Characteristics (All Enrolled Subjects)
| AGHD Patients (n = 53) | Matched Controls (n = 48) | |
|---|---|---|
| Sex, n, % | ||
| Male | 31 (58.5) | 30 (62.5) |
| Female | 22 (41.5) | 18 (37.5) |
| Race, n, %a | ||
| White | 49 (92.5) | 29 (60.4) |
| Black or African American | 2 (3.8) | 18 (37.5) |
| Asian | 2 (3.8) | 0 (0.0) |
| Other | 0 (0.0) | 1 (2.1) |
| Ethnicity, n, % | ||
| Hispanic or Latino | 11 (20.8) | 9 (18.8) |
| Not Hispanic or Latino | 42 (79.2) | 39 (81.3) |
| Age, y, n, % | ||
| Mean (SD) | 52 (13.4) | 53 (12.9) |
| Estrogen status, n, % | ||
| None | 12 (22.6) | 12 (25.0) |
| Oral | 9 (17.0) | 6 (12.5) |
| Patch | 1 (1.9) | 0 (0.0) |
| BMI, kg/m2, n, % | ||
| Lean (<25) | 7 (13.2) | 7 (14.6) |
| Overweight (≥25 and < 30) | 15 (28.3) | 13 (27.1) |
| Obese (≥30) | 31 (58.5) | 28 (58.3) |
| Mean | 32.1 (7.4) | 31.8 (7.1) |
| Etiology, n, %b | NA | |
| Pituitary adenoma | 34 (64.2) | |
| CNS tumors | 8 (15.1) | |
| Othersc | 18 (34.0) |
Abbreviation: CNS, central nervous system.
a
P < .05 between groups.
b
More than 1 cause may be applicable per patient.
c
Includes 11% head trauma, 4% empty sella, 6% childhood-onset GHD.