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LSD1 regulates triglyceride levels in hepatocytes. A and B, effects of transfection with NS or LSD1-shRNA plasmids in HEK293 cells on the mRNA levels of indicated genes in HEK293 by qRT-PCR (A) and the protein levels of endogenous FAS by immunoblotting (B). C–F, effects of LSD1 knockdown in HepG2 cells (C) or primary mouse hepatocytes (E) on the triglyceride levels (D and F). The data represent means ± S.D. (n = 3). *, p < 0.05; #, p < 0.01 versus NS.
