Mogat1 ASO increases fatty acid oxidation and suppresses lipogenesis.
A, rates of hepatocyte palmitate oxidation. Averages ± S.E. (error bars) for each group are shown. *, p < 0.05 versus LF and HTF-C controls. B, rates of de novo lipogenesis. *, p < 0.05 versus LF controls. **, p < 0.05 versus LF and HTF-C controls. C, rates of triglyceride synthesis and turnover. *, p < 0.05 versus LF controls. **, p < 0.05 versus LF and HTF-C controls. D, expression of genes encoding fatty acid oxidation and lipogenic enzymes. *, p < 0.05 versus controls. AU, arbitrary units.