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. 2014 Aug 7;4:735–740. doi: 10.1016/j.fob.2014.08.001

Fig. 1.

Fig. 1

Endogenous expression of SL3 shows bacteriocidal effects. (a) Expression of peptide SL3-His6X in H37Rv cells. (b) Significant reduction was observed in mycobacterial growth in the presence of endogenous SL3. Growth reduction was found to be statistically significant (Student’s T-test, p < 0.05). (c) Transmission electron micrographs of mycobacterial cells showing effects of endogenous SL3 on cell wall integrity and cell shape. (d) Representative colony images depicting change in colony surface. (e) Significant reduction was found in mycobacterial count inside THP-1 cells in the presence of endogenous SL3. All experiments were conducted in triplicates and repeated at least thrice. (t = 0) Defines the time at the beginning of phagocytosis. All readings were found to be statistically significant by applying Student’s T-test (p < 0.05).